BLOOD TYPES and COMPATIBILITY
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BLOOD TYPE COMPATIBILITY ACROSS A RANGE OF BLOOD TYPES - ABO BLOOD
TYPE MIXING AND RESULTS OF LATEST BLOOD RESEARCH AND COMPATIBLE
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Under the ABO Blood typing (grouping) scheme, there are two especially
important antigens called A and B. Every living human has either one or both
or neither of the red Blood cells. An individual with Blood group A is so
because he has antigen A. Antigen B makes a person's Blood group B. If a
person has both antigens, then they are in group AB. If they have neither,
the Blood group is O.
Antibodies against
these two antigens are found in Blood plasma. Some of the components of each
Blood type act against other components.
For example, Blood
groups A, B, AB and O have antigens A, B, A&B and 'none' respectively. The
antibodies are anti B, anti A, 'none' and anti A + anti B.
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AUTOLOGOUS BLOOD DONATION
During the
transfusion process, Blood matching must first be accurately done. How is
Blood matched? Exactly what is Blood compatability. Why is my Blood
compatible? For example if a person of Blood group A is given Blood from a
donor from Blood group B, the anti B antibodies will stick to the B antigens
on the donated red Blood cells entering their body. This makes a reaction
that can be fatal. Therefore, exact matching is critical; possibly the
difference between life and death!
".....
In the past, a person with blood type O negative blood was considered to
be a universal donor. It meant his or her blood could be given to
anyone, regardless of blood type, without causing a transfusion
reaction. This is no longer a relevant concept because of a better
understanding of the complex issues of immune reactions related to
incompatible donor blood cells."
- Mayo Clinic HealthOasis - Ask a Physician
08/09/2000 [full
text available HERE]
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Other than in extreme emergency conditions, donor Blood
is checked for compatibility with the recipient's Blood (cross-matched)
before it is transfused, regardless of Blood type. There are potentially
important Blood cell factors other than the A, B, AB and O Blood groups and
the Rh (Rhesus) factor that can lead to serious and in some cases,
irreversible problems.
There are
some good reasons for a husband to not donate Blood to his wife during
her childbearing years. During this time, a women who
plans to become pregnant, receiving Blood from her husband may pose a
small risk to the infants born of these pregnancies. If, after the Blood
transfusion the woman develops an antibody to an antigen on the father's
red Blood cells, and the subsequently born fetus inherits the father's
red cell antigen, the antibody from the mother may enter the Bloodstream
of the fetus causing destruction of fetal red Blood cells. This may
cause serious anemia in the fetus and excessive jaundice in the infant
after birth. This is a known major cause of brain damage. Special Blood
transfusions, using selected red Blood cells that do not have the
particular in-compatible and offending antigen, are available when this
condition is pre-diagnosed. Of course, we suggest autologous Blood
donation for the mother. However, for those mothers who are unable to
make an autologous donation, the decision to select her husband as a
donor should always take this risk under consideration, and specific
consultation with your pediatrician on this subject is essential.
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Having thoroughly confused the situation, study the following chart. It is
presented as a general guideline, and to help make the facts more clear. The
chart is correct, as a rule of thumb, barring anomalies
Blood Typing Systems other than ABO
World Distribution of ABO Blood Types Chart
Geogeaphic Study of ABO Blood Type
Distribution
African American Black Blood Donor Emergency
BLOOD
TYPE COMPATIBILITY CHART ** |
Blood
Type
of Recipient |
Donor
Can Be for..... |
Red
Cells |
Whole
Blood |
Plasma |
O + |
O +;
O - |
O +;
O - |
any
O; A; B or AB |
O - |
O - |
O - |
any
O; A; B or AB |
A + |
any
A +; A -;
O + or O - |
any
A + or A - |
any
A or AB |
A - |
any
A - or O - |
A - |
any
A or AB |
B + |
any
B +; B -;
O + or O - |
any
B + or B - |
any
B or AB |
B - |
any
B - or O - |
B - |
any
B or AB |
AB + |
any
AB +; AB -;
A +; A -;
B +; B -;
O +; or O- |
any
AB + or AB - |
any
AB |
AB - |
any
AB -;
A -; B -, or
O - |
AB - |
AB |
** NOTE:
Recent Blood research
indicates that, for instance, where a person with type O negative Blood was
considered to be a 'universal donor,' this may no longer be correct, because
of a better understanding of the complex issues of immune reactions related
to incompatible donor Blood cells.
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visiting BloodBook.com.
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last updated 03/10/2013
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